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| Rachid,Acir; Rezende,Lucila Stange; Moura,Suzelle Freitas de; Loffy,Paulo C.; Magalhães,Francisco Luiz Gomide M.. |
| Histoplasma capsulatum, a ground fungus, can infect humans, normally in endemic areas; the resulting disease can be asymptomatic or it can have a benign development, but in rare cases it can develop into a serious clinical condition and can even be fatal. Its most characteristic initial location is in the lungs, resembling tuberculosis, often accompanied by mediastinitis and an exuberant fibrotic response. The spread of this infection can be caused by the concomitance of another illness that alters the immunological balance. Sometimes such an association is not clear. Therefore, disseminated histoplasmosis is defined as a clinical condition where the fungus is present in more than one location. Common variable immunodeficiency is characterized by a... |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Disseminated histoplasmosis; Common variable immunodeficiency; Immunoglobulins. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000400007 |
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| Falci,Diego R.; Hoffmann,Elias R.; Paskulin,Diego D.; Pasqualotto,Alessandro C.. |
| Abstract The diagnosis of progressive disseminated histoplasmosis is often a challenge to clinicians, especially due to the low sensitivity and long turnaround time of the classic diagnostic methods. In recent years, studies involving a variety of non-culture-based diagnostic tests have been published in the literature. We performed a systematic review by selecting studies evaluating non-culture-based diagnostic methods for progressive disseminated histoplasmosis. We searched for articles evaluating detection of antibody, antigens, as well as DNA-based diagnostic methods. A comprehensive PUBMED, Web of Science, and Cochrane Library search was performed between the years 1956 and 2016. Case reports, review articles, non-human models and series involving... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Disseminated histoplasmosis; Non-culture; Enzyme immunoassay; Diagnostic tests. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000100007 |
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